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Biological Contaminants of Emerging Concern

BioCEC

BioCEC Home
PDF – Full Document
About ITRC
Navigating this Website
Introduction
1. Introduction
2. Background
3. BioCEC Guidance Sections
4. Case Study: Effects of Hurricane Helene on Western North Carolina
Process Guide
1. Identification of BioCEC
2. Actions to Take
Conceptual Exposure Model
1. Introduction
2. Building a Conceptual Exposure Model Using the Epidemiologic Triangle
3. Using a Conceptual Exposure Model
4. Conceptual Exposure Model Examples
5. Case Study: Using a Conceptual Exposure Model to Address a 2018 E. coli Outbreak Linked to Romaine Lettuce
Key Variables
1. Introduction
2. The Epidemiological Triangle
3. Considerations for Assessing Risks from BioCEC
4. Approaches to BioCEC Prioritization Strategies
5. Tools for Prioritization
6. Limitations and Knowledge Gap
Analytical Methods
Analytical Methods
1. Description of Analytical Methods
2. Microscopy
3. Culture-Based Methods
4. Flow Cytometry
5. Matrix-Assisted Laser Desorption Ionization Time-of-Flight (MALDI-TOF) Mass Spectrometry (MS)
6. Polymerase Chain Reaction (PCR)
7. Genomics
8. Fluorescence In Situ Hybridization (FISH)
9. Microbial Fingerprinting Methods
10. Isothermal Amplification Approaches
Monitoring Programs / Resource Hub
1. Introduction
2. Methods for Consolidating the Table of Resources and Current Monitoring Methods
3. Overall Findings from the Systematic Review of BioCEC Programs
4. Opportunities and Challenges to Leveraging Existing Programs to Improve BioCEC Monitoring
Case Studies
1. Case Study: Blastomycosis Outbreak
2. Case Study: 2018 Escherichia coli Outbreak Linked to Romaine Lettuce
3. Case Study: Quantitative Microbial Risk Assessment (QMRA)
References
Glossary
Acronyms
Acknowledgments

 

Biological Contaminants of Emerging Concern
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Acronyms

μm
micrometers
°C
degrees Celsius
°F
degrees Fahrenheit
ADEQ
Arizona Department of Environmental Quality
APHA
American Public Health Association
ArboNET
National arbovirus surveillance system
ASPHL
Alaska State Public Health Laboratory-Anchorage
AWWA
American Water Works Association
AZDA
Arizona Department of Agriculture
BioCEC
biological contaminants of emerging concern
CalEPA
California Environmental Protection Agency
CAFO
concentrated animal feeding operation
CalREDIE
California Reportable Disease Information Exchange
CCL
Contaminant Candidate List
CDC
Centers for Disease Control and Prevention
CEC
Contaminants of Emerging Concern
CEID
Center on Emerging Infectious Diseases
CEIP
California Emerging Infections Program
CEM
conceptual exposure model
CFU
colony forming units
CMR
Code of Massachusetts Regulations
CoE
Center of Excellence
CZVBD
Center for Zoonotic and Vector-borne Diseases
DALYs
disability-adjusted life years
DGGE
denaturing gradient gel electrophoresis
DNA
deoxyribonucleic acid
DNREC
Department of Natural Resources and Environmental Control
DPH
Department of Public Health
DPHL
Division of Public Health Laboratory
DPR
direct potable reuse
E. coli
Escherichia coli
EID
emerging infectious diseases
EIP
Emerging Infections Program
EMD
environmental molecular diagnostic
EMPOWER
Nevada Enabling the Management of Public Health Outcomes through Wastewater Resources
FC
flow cytometry
FDA
Food and Drug Administration
FEMA
Federal Emergency Management Agency
FISH
fluorescence in situ hybridization
FSIS
Food Safety and Inspection Service
g/kg
grams per kilogram
GAMN
General Assessment Monitoring Network
GPLN
Global Polio Laboratory Network
IDB
Infectious Diseases Branch
ITRC
Interstate Technology and Regulatory Council
LAC
Los Angeles County
LD50
lethal dose50
LRV
log10 reduction values
MALDI-TOF MS
matrix-assisted laser desorption ionization time-of-flight mass spectrometry
MassCPR
Massachusetts Consortium on Pathogen Readiness
MD ABCs
Maryland Active Bacterial Core
MDHHS
Michigan Departmen of Health and Human Services
mg/kg
milligrams per kilogram
mg/L
milligrams per liter
mL
milliliter
MLST
multilocus sequence typing
MRSA
methicillin resistant Staphylococcus aureus
NC OSBM
North Carolina Office of State Budget and Management
NDWAC
National Drinking Water Advisory Council
NETEC
National Emerging Special Pathogens Training and Education Center
NGS
next-generation sequencing
NIOSH
National Institute of Occupational Safety and Health
NJDEP
New Jersey Department of Environmental Protection
NNDSS
National Notifiable Diseases Surveillance System
NTU
nephelometric turbidity unit
NWSS
National Wastewater Surveillance System
NYSDOH
New York State Department of Health
PCCL
preliminary Contaminant Candidate List
PCR
polymerase chain reaction
PFGE
pulsed field gel electrophoresis
PHDM
Public Health: Delta and Menominee Counties
PLFA
phospholipid fatty acid
QC
quality control
QMRA
quantitative microbial risk assessment
qPCR
quantitative polymerase chain reaction
Redi-NET
Remote Emerging Disease Intelligence-NETwork
RFLP
restriction fragment length polymorphism
RNA
ribonucleic acid
SD
standard deviation
SRF
State Revolving Fund
STEC
Shiga toxin-producing E. coli
Task Force
Leafy Greens Food Safety Task Force
T-RFLP
terminal restriction fragment length polymorphism
USDA
United States Department of Agriculture
USEPA
United States Environmental Protection Agency
USEPA ORD
United States Environmental Protection Agency Office of Research and Development
USEPA OW
United States Environmental Protection Agency Office of Water
USGS
United States Geological Survey
UV
ultraviolet
VDEQ
Virginia Department of Environmental Quality
WaTCH-WV
Wastewater Testing for Community Health in West Virginia
WBDO
waterborne disease outbreak
WEF
Water Environment Federation
WHO
World Health Organization
WNC
Western North Carolina
WRD
Water Resources Department (City of Asheville, North Carolina)
WSLH
Wisconsin State Lab of Hygiene

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